The heart on the panties is just something Misato added since I though it would be something Misato would wear. Picture I used for sexy Add a Comment: Load All Images. Here she reminds me of Revy from Black Lagoon.
Did Misato want to have sex with Shinji?
Good job, BTW. Trust me when I say this, the story is much more beautiful. Yes, they have a romantic bond in the manga.
And actually, Rei is in no way related to Shinji in the manga. She's not even human! She's cloned from Lilith just like EVA